Δημοσιεύσεις (πρωτότυπες ερευνητικές εργασίες)


  1. Zakynthinos S, Vassilakopoulos T, Roussos Ch.  The load of inspiratory muscles in patients needing mechanical ventilation.  Am J Respir Crit Care Med 1995;152:1248-1255
  2. Zakynthinos S, Vassilakopoulos T, Zakynthinos E, Roussos Ch.  Accurate measurement of intrinsic positive end-expiratory pressure: How to detect and correct for expiratory muscle contraction.  Eur Respir J 1997;10:522-529. [accompanied by Editorial]
  3. Zakynthinos S, Vassilakopoulos T, Daniil Z, Zakynthinos E, Koutsoukos E, Katsouyianni E, Roussos Ch.  Pressure support ventilation in patients with ARDS.  Short-term effects of a servo-controlled modeJ Crit Care 1997; 12: 161-172
  4. Tzelepis G, Zakynthinos S, Vassilakopoulos T, Geroulanos S, Roussos Ch. Inspiratory maneuver effects on peak expiratory flow: Role of lung elastic recoil and expiratory pressure Am J Respir Crit Care Med 1997; 156: 1399-1404
  5. Vassilakopoulos T, Zakynthinos S, Roussos Ch. The tention - time index and the frequency / tidal volume ratio are the major pathophysiologic determinants of weaning failure and success. Am J Respir Crit Care Med 1998; 158: 378-385
  6. Zakynthinos S, Vassilakopoulos T, Mavrommatis A, Roussos C, Tzelepis G. Effects of different expiratory maneuvers on inspiratory muscle force output. Am J Respir Crit Care Med 1999; 159: 892-895
  7. Zakynthinos S, Vassilakopoulos T, Roussos C, Tzelepis G Correcting static intrinsic PEEP for expiratory muscle contraction:Validation of a new method. Am J Respir Crit Care Med 1999; 160: 785-790. [selected for the Critical Care Journal Club web site of the ATS assembly on Critical Care, October 1999]
  8. Vassilakopoulos T, Zakynthinos S. Can dynamic PEEPi be greater than static PEEPi ? Intensive Care Med 1999; 25:768
  9. Vassilakopoulos T, Zakynthinos S, Roussos C. Strenuous inspiratory resistive breathing produces proinflammatory cytokines and stimulates the hypothalamic - pituitary - adrenal axis in humans. Am J Physiol 1999; 277: R1013-R1019
  10. Zakynthinos E, Vassilakopoulos T, Roussos C, Zakynthinos S. Abnormal atrial and ventricular repolarisation resembling myocardial injury after tricyclic antidepressant drug intoxication. Heart 2000 83:353-354
  11. Vassilakopoulos T, Mastora Z, Katsaounou P, Doukas G, Klimopoulos S, Roussos C, Zakynthinos S. Contribution of pain to inspiratory muscle dysfunction after upper abdominal surgery. A randomized controlled trial. Am J Respir Crit Care Med 2000;161:1372-5
  12. Danou F, Paraskeva A, Vassilakopoulos T, Fassoulaki V. The analgesic efficacy of i.v tenoxicam as an adjunct to patient controlled analgesia in total abdominal hysterectomy. Anaesthesia & Analgesia 2000;90 (3):672-6
  13. Koutsoukou A, Armaganidis A, Stavrakaki C, Vassilakopoulos T, Lymperis A, Roussos C, Milic‑Emili J. Expiratory flow limitation and intrinsic PEEP in ARDS patients. Am J Respir Crit Care Med 2000;161:1590-1596
  14. Abrogast S, Vassilakopoulos T, Duvauchel JB, Fontanari M, Jammes Y Influence of oxygen supply on activation of group IV muscle afferents after low-frequency muscle stimulation. Muscle Nerve 2000; 23:1187-93
  15. Zakynthinos E, Vassilakopoulos T, Mpetsou A, Malagari E, Roussos C, Zakynthinos S Fever in patients with pacemaker: The necessity of early performing transesophageal echcardiography. Intensive Care Med 2000; 26:1157-8
  16. Zakynthinos S, Vassilakopoulos T, Zakynthinos E, Mavrommatis A, Roussos C. Contribution of expiratory muscle activity to dynamic intrinsic PEEP. Validation using the Campbell diagram. Am J Respir Crit Care Med 2000;162:1633-40. [accompanied by Editorial comment]
  17. Garinis G, Gorgoulis V, Mariatos G, Zacharatos P, Kotsinas A, Liloglou T, Foukas P, Kanavaros P, Kastrinakis N, Vassilakopoulos T, Vogiatzi T, Field J, Kittas C. Association of allelic loss at FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non small cell lung carcinomas (NSCLCs). The Journal of Pathology 2001, 193:55-65
  18. Zakynthinos E, Kontogianni D, Mpalafouta M, Vassilakopoulos T. Right ventricular outflow obstruction caused by non-small cell lung cancer. Int J Cardiol 2000, 75:313-314
  19. Vassilakopoulos T, Troupis T, Sotiropoulou C, Zacharatos P, Katsaounou P, Parthenis D, Noussia O, Troupis G, Zakynthinos S, Papiris S, Gorgoulis V. Diagnostic and prognostic significance of squamous cell carcinoma antigen in non small cell lung cancer. Lung Cancer 2001, 32:137-144
  20. Zakynthinos E, Vassilakopoulos T, Kontogianni D, Roussos C, Zakynthinos S. The role of Transesophageal Echocardiography in the early diagnosis of Catastrophic Antiphospholipid Syndrome. Int J Ιnternal Μedicine 2000 248(6): 519-524
  21. Zakynthinos E, Vassilakopoulos T, Fillipatos G, Roussos C, Zakynthinos S. Electrocardiographic and echocardiographic findings in elite water polo athletes. Scandinavian Journal of Medicine & Science in Sports 2001, 11:149-55
  22. Zakynthinos S, Vassilakopoulos T. Contribution of expiratory muscle activity to dynamic intrinsic positive end expiratory pressure. Am J Respir Crit Care Med 2001;163: 1278-1979
  23. Kosmidou I, Vassilakopoulos T, Xagorari A, Zakynthinos S, Papapetropoulos A, Roussos C. Production of interleukin-6 by skeletal myotubes: role of reactive oxygen species. Am J Respir Cell Mol Biol. 2002 May;26(5):587-93
  24. Zakynthinos EG, Vassilakopoulos T, Routsi C, Roussos C, Zakynthinos S. Early- and late-onset atrioventricular valve rupture after blunt chest trauma: the usefulness of transesophageal echocardiography. J Trauma. 2002 May;52(5):990-6
  25. Kalomenidis I, Orphanidou D, Papamichalis G, Vassilakopoulos T, Skorilas A, Rasidakis A, Papastamatiou H, Jordanoglou J, Roussos C. Combined expression of p53, Bcl-2, and p21WAF-1 proteins in lung cancer and premalignant lesions: association with clinical characteristics. Lung 2001;179(5):265-78
  26. Zakynthinos E, Vassilakopoulos T, Politis P, Daniil Z, Roussos C, Zakynthinos S. Uremic pericarditis with tamponade following prolonged continuous hemofiltration. Intensive Care Med. 2001 Dec;27(12):1958-9
  27. Zakynthinos E, Vassilakopoulos T, Kaltsas P, Malagari E, Daniil Z, Roussos C, Zakynthinos SG. Pulmonary hypertension, interstitial lung fibrosis, and lung iron deposition in thalassaemia major. Thorax. 2001 Sep;56(9):737-9
  28. Vassilakopoulos T, Katsaounou P, Karatza MH, Kollintza A, Zakynthinos S, Roussos C. Strenuous resistive breathing induces plasma cytokines: role of antioxidants and monocytes. Am J Respir Crit Care Med 2002;166:1572-8
  29. Vassilakopoulos T, Deckman G, Kebbewar M, Rallis G, Harfouche R, Hussain SN. Regulation of nitric oxide production in limb and ventilatory muscles during chronic exercise training. Am J Physiol Lung Cell Mol Physiol 2003; 284:L452-7
  30. Vassilakopoulos T, Karatza MH, Katsaounou P, Kollintza A, Zakynthinos S, Roussos C. Antioxidants attenuate the plasma cytokine response to exercise in humans. J Appl Physiol 2003;94:1025-32
  31. Vassilakopoulos T, Divangahi M, Rallis G, Kishta O, Comtois A, Hussain SNA Differential cytokine gene expression in the diaphragm in response to strenuous resistive breathing. Am J Respir Crit Care Med 2004; 170:154-161
  32. Vassilakopoulos T, Roussos C, Zakynthinos S. When are antioxidants effective in blunting the cytokine response to exercise? Med Sci Sports Exerc. 2005;37(2):342-3
  33. Sigala I, Kalomenidis I, Malagari K, Rontogianni D, Kapotsis G, Vassilakopoulos T, Roussos C, Papiris SA. Dry cough and dyspnoea rapidly increasing to respiratory failure in a male smoker.  Eur Respir J. 2005;25:1122-5
  34. Vassilakopoulos T, Roussos C, Zakynthinos S. Eur Respir J. 2005;25(6)1129-30 author reply to: Siafakas NM, Mitrouska I. The immune response to resistive breathing. Eur Respir J. 2005;25(6):1128-9
  35. Zakynthinos S, Routsi C, Vassilakopoulos T, Kaltsas P, Zakynthinos E, Kazi D, Roussos C. Differential cardiovascular responses during weaning failure: effects on tissue oxygenation and lactate. Intensive Care Med. 2005;31:1634-42
  36. Vassilakopoulos T, Routsi C, Sotiropoulou C, Bitsakou C, Stanopoulos I, Roussos C, Zakynthinos S. The combination of the load/force balance and the frequency/tidal volume can predict weaning outcome. Intensive Care Med. 2006; 32:684-91
  37. Hussain SN, Matar G, Barreiro E, Florian M, Divangahi M, Vassilakopoulos T. Modifications of proteins by 4-hydroxy-2-nonenal in the ventilatory muscles of rats. Am J Physiol Lung Cell Mol Physiol. 2006;290:L996-1003
  38. Zakynthinos S, Katsaounou P, Karatza M-H, Roussos C, Vassilakopoulos T.
    Antioxidants Increase the Ventilatory Response to Hyperoxic Hypercapnia. Am J Respir Crit Care Med. 2007;175(1):62-8
  39. Vassilakopoulos T, Govindaraju K, Parthenis D, Eidelman D, Watanabe Y, Hussain S. Nitric Oxide Production in the Ventilatory Muscles in Response to Acute Resistive Loading. Am J Physiol Lung Cell Mol Physiol 2007;292:L1013-1022
  40. Vassilakopoulos T, Roussos C, Zakynthinos S. The mixed venous oxygen saturation response to weaning from mechanical ventilation. Resp Care 2007;52:64
  41. Koroneos A, Politis P, Malachias S, Manolis A, Vassilakopoulos T. End-inspiratory occlusion maneuver during transesophageal echocardiography for Patent Foramen Ovale detection in Intensive Care Unit Patients. Intensive Care Med. 2007;33(8):1458-62
  42. Pyriochou A, Tsigkos S, Vassilakopoulos T, Cottin T, Zhou Z, Gourzoulidou E, Roussos C, Waldmann H, Giannis A, Papapetropoulos A. Anti-angiogenic properties of a sulindac analogue. Br J Pharmacol. 2007;152:1207-14
  43. Pyriochou A, Vassilakopoulos T, Zhou Z, Papapetropoulos A. cGMP-dependent and -independent angiogenesis-related properties of nitric oxide. Life Sci. 2007 Nov 10;81(21-22):1549-54
  44. Pratikaki M, Platsouka E, Sotiropoulou C, Vassilakopoulos T, Paniara O, Roussos C, Routsi C. Risk factors for and influence of bloodstream infections on mortality: a 1-year prospective study in a Greek intensive-care unit. Epidemiol Infect. 2008;16:1-9.
  45. Simoes DC, Vassilakopoulos T, Toumpanakis D, Petrochilou K, Roussos C, Papapetropoulos A.  Angiopoietin-1 protects against airway inflammation and hyperreactivity in asthma. Am J Respir Crit Care Med. 2008;177:1314-21
  46. Parthenis D Skevis K, Stathopoulos V, Bellenis I, Vassilakopoulos T. Post- Laparoscopic Iatrogenic Pseudo aneurysms of the Arteries of the Peritoneal and Retroperitoneal Space Case Report and Review of the Literature.  Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 2009 Apr;19(2):90-7
  47. Porfyridis I, Kalomenidis I, Psallidas I, Stratakos G, Roussos C, Vassilakopoulos T, Stathopoulos GT. Etanercept-induced pleuropericardial lupus-like syndrome. Eur Respir J. 2009;33:939-41
  48. Toumpanakis D, Karatza MH, Katsaounou P, Roussos C, Zakynthinos S, Papapetropoulos A, Vassilakopoulos T. Antioxidant supplementation alters cytokine production from monocytes. J Interferon Cytokine Research 2009; 29(11):741-8
  49. Kim HC, Mofarrahi M, Vassilakopoulos T, Maltais F, Sigala I, Debigare R, Bellenis I, Hussain SN. Expression and functional significance of nicotinamide N-methyl transferase in skeletal muscles of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010;181(8):797-805
  50. Hussain SN, Mofarrahi M, Sigala I, Kim HC, Vassilakopoulos T, Maltais F, Bellenis I, Chaturvedi R, Gottfried SB, Metrakos P, Danialou G, Matecki S, Jaber S, Petrof BJ, Goldberg P. Mechanical Ventilation-induced Diaphragm Disuse in Humans Triggers Autophagy. Am J Respir Crit Care Med. 2010;182:1377-86
  51. Hillas G, Vassilakopoulos T, Plantza P, Rasidakis A, Bakakos P. C-reactive protein and procalcitonin as predictors of survival and septic shock in ventilator-associated pneumonia. Eur Respir J. 2010;35:805-11[accompanied by Editorial]  
  52. Makris AC, Sotzios Y, Zhou Z, Makropoulou M, Papapetropoulos N, Zacharatos P, Pyriochou A, Roussos C, Papapetropoulos A, Vassilakopoulos T. Nitric oxide stimulates interleukin-6 production in skeletal myotubes. J Interferon CytokineRes. 2010;30(5):321-7
  53. Toumpanakis D, Kastis GA, Zacharatos P, Sigala I, Michailidou T, Kouvela M, Glynos C, Divangahi M, Roussos C, Theocharis SE, Vassilakopoulos T. Inspiratory Resistive Breathing Induces Acute Lung Injury. Am J Respir Crit Care Med. 2010; 182:1129-1136  
  54. Sigala I, Zacharatos P, Toumpanakis D, Michailidou T, Noussia O, Theocharis S, Roussos C, Papapetropoulos A, VassilakopoulosT. MAPKs and NF-kB differentially regulate cytokine expression in the diaphragm in response to resistive breathing: the role of oxidative stress. AmJPhysiolRegulIntegrComp Physiol. 2011; 300(5):R1152-62
  55. Nunnally ME, Jaeschke R, Bellingan GJ, Lacroix J, Mourvillier B, Rodriguez-Vega GM, Rubertsson S, VassilakopoulosT, Weinert C, Zanotti-Cavazzoni S, Buchman TG. Targeted temperature management in critical care: A report and recommendations from five professional societies. Crit Care Med. 2011;39:1113-1125
  56. Sigala I, Zacharatos P, Boulia S, Toumpanakis D, Michailidou T, Parthenis D, Roussos C, Papapetropoulos A, Hussain SN, Vassilakopoulos T. Nitric oxide regulates cytokine induction in the diaphragm in response to inspiratory resistive breathing. J Appl Physiol. 2012;113:1594-603
  57. Kastis GA, Toumpanakis D, Loverdos K, Anaplioti A, Samartzis A, Argyriou P, Loudos G, Karavana V, Tzouda V, Datseris I, Rontogianni D, Roussos C, Theocharis SE, Vassilakopoulos T. Dose- and time-dependent effects of lipopolysaccharide on technetium-99-m-labeled diethylene-triamine pentaacetatic acid clearance, respiratory system mechanics and pulmonary inflammation. Exp Biol Med (Maywood). 2013;238:209-22
  58. Karakou E, Glynos C, Samara KD, Msaouel P, Koutsilieris M VassilakopoulosT. Profile of Endocrinological Derangements Affecting PSA Values in Patients with COPD. In Vivo 2013;27(5):641-9.
  59. Glynos C, Dupont L, Vassilakopoulos T,  Papapetropoulos A, Brouckaert P, Giannis A, Joos GF, Bracke KR, Brusselle G. The role of soluble guanylyl cyclase in Chronic Obstructive Pulmonary Disease Am J Respir Crit Care Med 2013;188(7):789-99
  60. Mofarrahi M, Sigala I, Vassilakopoulos T, Harel S, Guo Y, Debigare R, Maltais F, Hussain SN. Angiogenesis-related factors in skeletal muscles of COPD patients: roles of angiopoietin-2. J Appl Physiol (1985). 2013 May;114(9):1309-18
  61. Glynos C, Toumpanakis D, Loverdos C, Karavana V, Zhou Z, Magkou C, Theocharis S, Dettoraki M, Perlikos F, Michailidou T, Paulidou T, Kotsikoris V, Topouzis S, Brouckaert P, Giannis A, Papapetropoulos A, Vassilakopoulos T. Guanylyl cyclase ameliorates resistive breathing induced lung injury and inflammation Am J Respir Cell Mol Biol 2015 Jun;52(6):762-71
  62. Toumpanakis D, Noussia O, Sigala I, Loverdos K, Zacharatos P, Karavana V, Tatiana Michailidou T, Theocharis S, Vassilakopoulos T. Inspiratory resistive breathing induces MMP-9 and MMP-12 expression in the lung Am J Physiol Lung Cell Mol Physiol 2015;308(7):L683-92.
  63. Hillas G, Toumpanakis D, Litsiou E, Nikolakopoulou S, Sagris K, Vassilakopoulos T. Controlled Mechanical Ventilation Attenuates the Systemic Inflammation of Severe Chronic Obstructive Pulmonary Disease Exacerbations Am J Respir Crit Care Med 2016;193(6):696-8.
  64. Bibli SI, Andreadou I, Glynos C, Chatzianastasiou A, Toumpanakis D, Zakynthinos S, Vasilakopoulos T, Iliodromitis EK, Papapetropoulos A. Exposure to cigarette smoke abrogates the beneficial effect of ischemic postconditioning. Am J Physiol Heart Circ Physiol. 2016 Nov 1;311(5):H1321-H1332.
  65. Loverdos K, Toumpanakis D, Litsiou E, Karavana V, Glynos C, Magkou C, Theocharis S, Vassilakopoulos T. The differential effects of inspiratory, expiratory, and combined resistive breathing on healthy lung. Int J Chron Obstruct Pulmon Dis. 2016;11:1623-38.
  66. Kourlaba G, Hillas G, Vassilakopoulos T, Maniadakis N. The disease burden of chronic obstructive pulmonary disease in Greece. Int J Chron Obstruct Pulmon Dis 2016;11:2179-2189.
  67. Souliotis K, Kousoulakou H, Hillas G, Bakakos P, Toumbis M, Loukides S, Vassilakopoulos T. Direct and Indirect Costs of Asthma Management in Greece: An Expert Panel Approach. Front Public Health. 2017 Apr 5;5:67.
  68. Gourzoulidis G, Kourlaba G, Kakisis J, Matsagkas M, Giannakoulas G, Gourgoulianis KI, Vassilakopoulos T, Maniadakis N. Cost-Effectiveness Analysis of Rivaroxaban for Treatment of Deep Vein Thrombosis and Pulmonary Embolism in Greece. Clin Drug Investig. 2017 Jun 12. doi: 10.1007/s40261-017-0540-1. [Epub ahead of print] PubMed PMID: 28608312.
  69. Souliotis K, Kousoulakou H, Hillas G, Tzanakis N, Toumbis M, Vassilakopoulos T. The direct and indirect costs of managing chronic obstructive pulmonary disease in Greece. Int J Chron Obstruct Pulmon Dis. 2017;12:1395-1400.
  70. Toumpanakis D, Loverdos K, Tzouda V, Vassilakopoulou V, Litsiou E, Magkou C, Karavana V, Pieper M, Vassilakopoulos T. Tiotropium bromide exerts anti-inflammatory effects during resistive breathing, an experimental model of severe airway obstruction. Int J Chron Obstruct Pulmon Dis. 2017;12:2207-2220.
  71. Toumpanakis D, Vassilakopoulou V, Sigala I, Zacharatos P, Vraila I, Karavana V, Theocharis S, Vassilakopoulos T. The role of Src & ERK1/2 kinases in inspiratory resistive breathing induced acute lung injury & inflammation. Respiratory Research 2017 Dec 13;18(1):209. doi: 10.1186/s12931-017-0694-7.
  72. Asimakos A, Toumpanakis T, Karatza MH, Vasileiou S, Katsaounou P, Mastora Z, Vassilakopoulos T. The immune cell response to strenuous resistive breathing: comparison with whole body exercise, and the effects of antioxidants Int J Chron Obstruct Pulmon Dis 2018;13:529-545.
  73. Toumpanakis D, Vassilakopoulou V, Mizi E, Chatzianastasiou A, Loverdos K, Vraila I, Perlikos F, Tsoukalas D, Giannakopoulou CE, Sotiriou A, Dettoraki M, Karavana V, Vassilakopoulos T. p38 Inhibition Ameliorates Inspiratory Resistive Breathing-Induced Pulmonary Inflammation. Inflammation 2018:DOI: 10.1007/s10753-018-0831-6


Άρθρα Σύνταξης 

  1. Ηussain SNA & Vassilakopoulos T. Ventilator induced cachexia Am J Respir Crit Care Med 2002;166:1307-8
  2. Vassilakopoulos T, Zakynthinos S. When mechanical ventilation mimics nature. Crit Care Med.2008;36:1009-11.
  3. Vassilakopoulos T. Understanding wasted/ineffective efforts in mechanically ventilated COPD patients using the Campbell diagram. Intensive Care Med. 2008;34:1336-9.
  4. Vassilakopoulos T. The patient-ventilator interaction has a third player: the endotracheal tube. Chest. 2009;136:957-9.
  5. Artigas A, Pelosi P, Dellweg D, Brochard L, Ferrer M, Geiseler J, Larsson A, Nava S, Navalesi P, Noël JL, Orfanos S, Palange P, Schoenhofer B, Vassilakopoulos T, Simonds A; ERS Educational Task Force on Respiratory Critical Care HERMES Respiratory critical care HERMES syllabus: defining competencies for respiratory doctors. Eur Respir J. 2012;39:1294-7.
  6. Artigas A, Noël JL, Brochard L, Busari JO, Dellweg D, Ferrer M, Geiseler J, Larsson A, Nava S, Navalesi P, Orfanos S, Palange P, Pelosi P, Rohde G, Schoenhofer B, Vassilakopoulos T, Simonds AK. Defining a training framework for clinicians in respiratory critical care. Eur Respir J. 2014 Sep;44(3):572-7.
  7. Vassilakopoulos T. Ultrasonographic Monitoring of the Diaphragm during Mechanical Ventilation: The Vital Pump Is Vivid, Plastic, and Vulnerable. Am J Respir Crit Care Med. 20151;192(9):1030-2.
  8. Vassilakopoulos T. Respiratory muscle wasting in the ICU: is it time to protect the diaphragm? Thorax 2016;71:5 397-398
  9. Vassilakopoulos T, Petrof B. A stimulating approach to ventilator-induced diaphragmatic dysfunction. Am J Respir Crit Care Med 2017;195(3):281-282.
  10. Sigala I, Vassilakopoulos T. Diaphragmatic ultrasound as a monitoring tool in the intensive care unit. Ann Transl Med. 2017 Feb;5(4):79.


Άρθρα Ανασκόπησης:


  1. Vassilakopoulos T,Zakynthinos S, Roussos Ch.  Respiratory muscles and weaning failure. Eur Respir J 1996;9:2383-2400.
  2. Vassilakopoulos T, Zakynthinos S, Roussos Ch. Respiratory muscles and ventilatory failure. Monaldi Arch Chest Dis 1996; 6:489-498.
  3. Vassilakopoulos T, Zakynthinos S, Roussos Ch. Factors determining the weaning outcome. Monaldi Arch Chest Dis 1998; 53: 365-371.
  4. Vassilakopoulos T, Zakynthinos E, Roussos C, Zakynthinos S. Respiratory muscles in heart failure. Monaldi Arch Chest Dis 1999; 54:150-153
  5. Vassilakopoulos T, Roussos C, Zakynthinos S. Weaning from mechanical ventilation. J Crit Care 1999; 39-62.
  6. Zakynthinos S, Vassilakopoulos T.  Intensive and high-dependency care medicine in Greece. Monaldi Arch Chest Dis (invited review) 1999; 54:5, 438-440
  7. Vassilakopoulos T & Petrof B. Ventilator-induced diaphragmatic dysfunction Am J Respir Crit Care Med 2004; 169: 336-341 [unsolicited critical care perspective]
  8. Vassilakopoulos T, Roussos C, Zakynthinos S. The immune response to resistive breathing. Eur Respir J 2004;24:1033-43.
  9. Vassilakopoulos T, Roussos C, Zakynthinos S. Is loaded breathing an inflammatory stimulus? Cur Opin Crit Care 2005;11:1-9.
  10. Vassilakopoulos T, Zakynthinos S, Roussos C. Bench-to-bedside review: Weaning failure- should we rest the respiratory muscles with controlled mechanical ventilation? Crit Care 2005 Nov 22;10(1):204
  11. VassilakopoulosT, Hussain S. ventilatory muscle activation and inflammation: cytokines, reactive oxygen species and nitric oxide. J Appl Physiol 2007;102:1687-1695.
  12. Vassilakopoulos T. Ventilator-induced diaphragmatic dysfunction: The clinical relevance of animal models. Intensive Care Med. 2008;34:7-16
  13. Hillas G, Nikolakopoulou S, Hussain S, Vassilakopoulos T. Antioxidants and mucolytics in COPD management: when (if ever) and in whom? Current Drug Targets. 2013;14:225-34
  14. Vassilakopoulos T, Toumpanakis D. Can resistive breathing injure the lung? Implications for COPD exacerbations. Int J Chron Obstruct Pulmon Dis 2016;11 2377-2384.
  15. Rossi A, Butorac-Petanjek B, Chilosi M, Cosío BG, Flezar M, Koulouris N, Marin J, Miculinic N, Polese G, Samaržija M, Skrgat S, Vassilakopoulos T, Vukić-Dugac A, Zakynthinos S, Miravitlles M.  Chronic obstructive pulmonary disease with mild airflow limitation: current knowledge and proposal for future research – a consensus document from six scientific societies. Int J Chron Obstruct Pulmon Dis. 2017;12 2593–2610.
  16. Huertas A, Guignabert C, Barberà JA, Bärtsch P, Bhattacharya J, Bhattacharya S, Bonsignore MR, Dewachter L, Dinh-Xuan AT, Dorfmüller P, Gladwin MT, Humbert M, Kotsimbos T, Vassilakopoulos T, Sanchez O, Savale L, Testa U, Wilkins MR. Pulmonary vascular endothelium: the orchestra conductor in respiratory diseases:  Highlights from basic research to therapy. Eur Respir J. 2018 Apr 4;51(4). pii:1700745. doi: 10.1183/13993003.00745-2017. Print 2018 Apr. Review. PubMed PMID:29545281.



Κεφάλαια σε συλλογικούς τόμους:


  1. Vassilakopoulos T, Zakynthinos S, Roussos Ch. Weaning from ventilators. In: Current practice in critical illness.  D Ryan (ed), Chapman and Hall, 1996, pp 152-192.


  1. Vassilakopoulos T, Zakynthinos S, Roussos Ch. Muscle function: Basic concepts.  In: Physiologic basis of ventilator support.  Marini JJ, Slutsky A (eds), Marcel Dekker, New York, 1998. pp 103-152.


  1. Vassilakopoulos T, Zakynthinos S, Roussos Ch. The conventional approach to weaning from mechanical ventilation.  Eur Respir Mon 1998; 8: 266-298.


  1. Vassilakopoulos T, Roussos C (Chapter 28).Neuromuscular respiratory failure. In: Clinical Critical Care Medicine. Albert, Slutsky, Ranieri, Takala, Torres (editors), Elsevier 2006 pp 275-282


  1. Vassilakopoulos T, Roussos C. Physiology and testing of respiratory muscles (chapter 8). In: Clinical Respiratory Medicine. Albert, Spiro, Jett (editors) 3rd edition, Mosby, Elsevier 2008 pp 135-146.


  1. Vassilakopoulos T, Sigala I. Roussos C. Muscle Function (chapter 8). In: Mechanical Ventilation. Clinical applications and pathophysiology. Papadakos, Lachmann (editors), Saunders, Elsevier 2008 pp 111-138


  1. Vassilakopoulos T. Ventilator-induced diaphragm dysfunction (Chapter 43). In: Principles and Practice of Mechanical Ventilation, 2nd edition. Tobin MJ (editor), McGraw Hill pp 963-972.


  1. Katsaounou P, Vassilakopoulos T. Severe Asthma exacerbation (chapter 140). In: Civetta, Taylor & Kirby's critical care 4th  edition Andrea Gabrielli, A. Joseph Layon, Mihae YUU (editors), Elsevier, p.2110-2133.


  1. Ischaki E, Vassilakopoulos T. Pathophysiology of weaning failure (chapter 57) In: Non-invasive Ventilation and Weaning: Principles and Practice, Mark Elliott, Stefano Nava and Bernd Schoanhofer (editors). Hodder Education pp 521-529.


  1. Vassilakopoulos T. Ventilator-induced diaphragm dysfunction (Chapter 43). In: Principles and Practice of Mechanical Ventilation, 3rd edition. Tobin MJ (editor), McGraw Hill pp 1023-1039.


  1. Kokkoris S, Vassilakopoulos T, Hussain S. Oxidative Stress in Exercise and Training. In: Principles of Free Radical Biomedicine, Volume III Editors: K. Pantopoulos and H. M. Schipper ©2012 Nova Science Publishers, Inc (Chapter 15) pp 351-365


  1. Vassilakopoulos T. Control of Ventilation and Respiratory Muscles (Chapter 6). In: Clinical Respiratory Medicine. Albert, Spiro, Jett (editors) 4th edition, Elsevier 2012 pp 50-62.





    1. Theodoros Vassilakopoulos.

Multiple choice questions in respiratory medicine

(SPIR ALLI 11/6 202-14-4594, pp 1-136, 2006)


    1. Ioanna Sigala, Giorgos Hillas, Theodoros Vassilakopoulos

Multiple choice questions in COPD

(SPIR ALLI 04/10 DC000761, pp 1-104, 2010)


    1. Theodoros Vassilakopoulos.

Acid-Base Disorders

(Zevelekakis publications ISBN 978-960-89952-2-2, pp 1-229, 2011)


    1. Theodoros Vassilakopoulos.

Basic principles of mechanical ventilation

(Zevelekakis publications ISBN 9789608995260, pp 1-104, 2013).